In the game between the Arizona Cardinals and Atlanta Falcons on Sunday, Dec. 21 at 4:05 p.m. ET, our projection model expects the Cardinals to emerge victorious. Wanting predictions on the final score, spread, and point total, too? Find a full game projection below.
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Falcons vs. Cardinals Game Info and TV Channel
- When: Sunday, December 21, 2025 at 4:05 p.m. ET
- Where: State Farm Stadium in Glendale, Arizona
- TV: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Listen to the game on 92-9 The Game
Falcons vs. Cardinals Odds and Betting Info
- Spread favorite: Falcons (-2.5)
- Moneyline: Falcons (-153), Cardinals (+128)
- Total: 48.5 points
Falcons vs. Cardinals Prediction
- Pick ATS: Cardinals (+2.5)
- Pick OU: Under (48.5)
Prediction:
Cardinals 24 - Falcons 23
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Falcons vs. Cardinals Betting Insights
- The Falcons have compiled a 7-7-0 ATS record so far this year.
- The Cardinals have covered six times in 14 matchups with a spread this season.
- Arizona has covered the spread twice this season (2-3 ATS) when playing as at least 2.5-point underdogs.
- So far this season, seven out of the Falcons' 14 games have hit the over.
- In 2025, nine Cardinals games have gone over the point total.
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