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The Clemson Tigers (20-8, 10-5 ACC) will look to end a four-game losing streak when they host the Louisville Cardinals (20-8, 9-6 ACC) on February 28, 2026 at Littlejohn Coliseum.
Saturday's matchup between the Cardinals and the Tigers features a close line of Louisville -1.5. The over/under for the matchup is set at 146.5.
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Louisville vs. Clemson Odds and Game Info
- Game day: Saturday, February 28, 2026
- Game time: 2 p.m. ET
- TV channel: ESPN2
- Location: Clemson, South Carolina
- Arena: Littlejohn Coliseum
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Louisville vs. Clemson Odds and Prediction
- Spread favorite: Louisville (-1.5)
- Moneyline: Louisville (-137), Clemson (+113)
- Total: 146.5 points
Pick ATS:Louisville (-1.5)
- Pick OU: Over (146.5)
- Prediction: Louisville 76, Clemson 73
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Louisville vs. Clemson Comparison
| Louisville Rank | Louisville Stat | Clemson Stat | Clemson Rank | |
|---|---|---|---|---|
| 16th | 86.4 | Points Scored | 74.5 | 221st |
| 125th | 72 | Points Allowed | 65.6 | 18th |
| 21st | 17.5 | Assists | 13 | 250th |
| 257th | 11.8 | Turnovers | 9 | 23rd |
| 76th | 47% | Field Goal % | 45.8% | 141st |
| 51st | 41.6% | Field Goal % Allowed | 41.2% | 41st |
Louisville Key Players
- Mikel Brown Jr. leads the Cardinals in points and assists per game, scoring 18.9 points and distributing 4.8 assists.
- Sananda Fru leads Louisville in rebounding, grabbing 6.4 rebounds per game while also scoring 9.6 points a contest.
- Ryan Conwell makes more threes per game than any other member of the Cardinals, knocking down shots from beyond the arc at a clip of 3.3 per contest.
- The Louisville steals leader is Conwell, who averages 1.2 takeaways per game, while its blocks leader is Fru, who compiles 1.4 rejections per contest.
Clemson Key Players
- RJ Godfrey is at the top of the Tigers scoring leaderboard with 11.5 points per game. Godfrey also pulls down five rebounds and dishes out 1.6 assists per game.
- The Clemson leaders in rebounding and assists are Carter Welling with 5.6 rebounds per game (also adding 10.3 points and 1.3 assists per game) and Dillon Hunter with three assists per game (also tacking on 7.7 points and 3.9 rebounds per game).
- Jestin Porter is the top shooter from distance for the Tigers, hitting 1.8 threes per game.
- Clemson's leader in steals is Porter (1.3 per game), and its leader in blocks is Godfrey (0.6 per game).
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